Which cholinergic antagonist can be used to counteract cholinergic crisis induced by Edrophonium?

Atropine is the correct choice for counteracting a cholinergic crisis induced by Edrophonium. Edrophonium is a short-acting acetylcholinesterase inhibitor that increases the levels of acetylcholine in the synaptic cleft. In cases of cholinergic crisis, where excessive acetylcholine leads to overstimulation of the cholinergic receptors, atropine acts as a competitive antagonist at muscarinic receptors. By blocking these receptors, atropine effectively reduces the symptoms associated with cholinergic overload, such as salivation, lacrimation, urination, diarrhea, gastrointestinal distress, and muscle spasms. This makes atropine a critical antidote in managing cholinergic toxicity.

Other options lack the specific mechanism needed to effectively counteract the effects of excessive acetylcholine. Scopolamine, while also a muscarinic antagonist, is primarily used for motion sickness and does not have the acute reversing capabilities of atropine in cholinergic crisis scenarios. Curare is a neuromuscular blocker that could potentiate the effects of a cholinergic crisis rather than counteract them. Succinylcholine is a depolarizing neuromuscular blocker used in anesthesia, which also would not alleviate cholinergic