Which cholinergic agent serves to enhance memory function?

Study for the Pharmacology Cholinergic Agents Test. Test your knowledge with flashcards and multiple choice questions, each question provides hints and detailed explanations. Master your exam preparation today!

Donepezil is a cholinergic agent specifically designed to enhance memory function, particularly in patients with Alzheimer's disease. It works as a reversible inhibitor of the enzyme acetylcholinesterase, which breaks down the neurotransmitter acetylcholine in the synaptic cleft. By inhibiting this enzyme, donepezil increases the levels of acetylcholine available for neurotransmission. Enhanced cholinergic activity is associated with improved cognitive function, such as memory and learning, making donepezil effective for addressing symptoms of memory impairment.

Other agents listed have different mechanisms and uses. For instance, pilocarpine is primarily used to treat dry mouth and glaucoma by stimulating muscarinic receptors but does not directly enhance cognitive function. Atropine is an anticholinergic agent that blocks acetylcholine, which would oppose memory enhancement. Carbachol is a direct-acting cholinergic agonist used mainly for glaucoma and does not specifically target memory enhancement like donepezil does. Hence, donepezil stands out as the appropriate choice for enhancing memory function.

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