What are the three side effects associated with Physostigmine?

Physostigmine is a reversible inhibitor of the enzyme acetylcholinesterase, leading to increased cholinergic activity within the nervous system. The side effects associated with this medication are primarily due to the enhanced effects of acetylcholine due to the inhibition of its breakdown.

Cholinergic effects, which include symptoms such as excessive salivation, lacrimation, urination, defecation, gastrointestinal distress, and muscle twitching, are significant and often arise from increased acetylcholine levels. This overstimulation of cholinergic receptors can also lead to convulsions as a result of CNS overstimulation. Additionally, in severe cases of cholinergic excess, paralysis may occur, typically due to the overwhelming activation of nicotinic receptors at the neuromuscular junction.

By highlighting these side effects, it becomes clear why this option reflects the physiological consequences of enhanced cholinergic activity due to Physostigmine usage. Other options might mention symptoms that do not typically associate with the pharmacological profile of Physostigmine or may not accurately represent the mechanism of action or side effects of cholinergic agents.