What are the main side effects of Pilocarpine?

The main side effects of Pilocarpine are indeed associated with its pharmacological action as a cholinergic agent. Pilocarpine is a muscarinic agonist primarily used to treat dry mouth (xerostomia) and ocular conditions like glaucoma. The cholinergic stimulation it promotes can lead to various side effects related to increased activity in glandular secretions as well as effects on the eyes and facial muscles.

Blurred vision can occur due to increased secretion in the eye and changes in refraction that result from pupillary constriction (miosis) and ciliary muscle contraction. Night blindness may result from changes in the ability of the pupil to dilate appropriately in low-light conditions. Brow ache, or discomfort in the forehead or brow area, is often reported because of the ciliary muscle contraction. Rarely, excessive doses or sensitivity to Pilocarpine can lead to symptoms akin to poisoning, such as excessive salivation, lacrimation, urination, diarrhea, gastrointestinal distress, and muscle trembling.

The other options list side effects that are either not commonly associated with Pilocarpine or relate to other medication types or medical conditions, making them less relevant in the context of this specific drug's effects.